Date of submission: 27/05/2022

Malignant Colon Neoplasm

CRL-1784

Model characterisation

Provided by

Charles River Laboratories

View data at CRLContact CRL

License: EMBL-EBI

Patient / Tumour Metadata

  • Patient Sex
    male
  • Patient Age
    60 - 69
  • Patient Ethnicity
    White
  • Tumour Type
    Metastatic
  • Cancer Grade
    G2
  • Cancer Stage
    M1
  • Primary Site
    colon
  • Collection Site
    liver

PDX model engraftment

PDX model engraftment
HOST STRAIN NAMESITETYPEMATERIALMATERIAL STATUSPASSAGE
nmri
SubcutaneousHeterotopicTissue FragmentFresh/frozen0,8

Model quality control

Model quality control
TECHNIQUEDESCRIPTIONPASSAGE
Histologyhigh concordance between xenograft passages<5,8,20

Immune markers

HLA

HLA
SAMPLE IDHLA-AHLA-BHLA-CHLA-DRB1
CXF_1784-1174HLA-A*24:2, HLA-A*24:2
HLA-B*51:1, HLA-B*51:1
HLA-C*3:3, HLA-C*3:3
HLA-DRB1*4:1, HLA-DRB1*4:1

Patient treatment

Patient treatment
TREATMENTDOSERESPONSE
Fluorouracil
ChEMBLPubChem
Oxaliplatin
ChEMBLPubChem
Leucovorin
ChEMBLPubChem
not provided
not provided
not provided
Not Provided
Not Provided
Not Provided