Malignant Colon Neoplasm - PDX

CRL-2127

Model characterisation

Provided by

Charles River Laboratories

View data at CRLContact CRL

License: EMBL-EBI

Patient / Tumour Metadata

  • Patient Sex
    female
  • Patient Age
    80 - 89
  • Patient Ethnicity
    White
  • Tumour Type
    Metastatic
  • Cancer Grade
    G3
  • Cancer Stage
    T3N0
  • Primary Site
    colon
  • Collection Site
    liver

PDX model engraftment

PDX model engraftment
HOST STRAIN NAMESITETYPEMATERIALMATERIAL STATUSPASSAGE
nmri
SubcutaneousHeterotopicTissue FragmentFresh/frozen0,5

Model quality control

Model quality control
TECHNIQUEDESCRIPTIONPASSAGE
Histologyhigh concordance between xenograft passages<5,5,14

Immune markers

HLA

HLA
SAMPLE IDHLA-AHLA-BHLA-CHLA-DQB1HLA-DRB1
A1955-014HLA-A*68:1, HLA-A*1:1
HLA-B*8:1, HLA-B*40:1
HLA-C*7:1, HLA-C*3:4
HLA-C*7:6, HLA-C*3:4
HLA-DQB1*5:1, HLA-DQB1*5:1
HLA-DRB1*1:1, HLA-DRB1*1:1