Malignant Colon Neoplasm - PDX

CRL-2129

Model characterisation

Provided by

Charles River Laboratories

View data at CRLContact CRL

License: EMBL-EBI

Patient / Tumour Metadata

  • Patient Sex
    female
  • Patient Age
    80 - 89
  • Patient Ethnicity
    White
  • Tumour Type
    Metastatic
  • Cancer Grade
    G1
  • Cancer Stage
    T3N2
  • Primary Site
    colon
  • Collection Site
    liver

PDX model engraftment

PDX model engraftment
HOST STRAIN NAMESITETYPEMATERIALMATERIAL STATUSPASSAGE
nmri
SubcutaneousHeterotopicTissue FragmentFresh/frozen0,2,7

Model quality control

Model quality control
TECHNIQUEDESCRIPTIONPASSAGE
Histologyhigh concordance between xenograft passages<5,3,13

Immune markers

HLA

HLA
SAMPLE IDHLA-AHLA-BHLA-C
A1955-016HLA-A*3:1, HLA-A*66:1
HLA-B*41:2, HLA-B*35:3
HLA-C*4:1, HLA-C*17:1

Patient treatment

Patient treatment
TREATMENTDOSERESPONSE
Capecitabinenot providedNot Provided