Lung Small Cell Carcinoma - PDX

CRL-650

Model characterisation

Provided by

Charles River Laboratories

View data at CRLContact CRL

License: EMBL-EBI

Patient / Tumour Metadata

  • Patient Sex
    male
  • Patient Age
    60 - 69
  • Patient Ethnicity
    White
  • Tumour Type
    Metastatic
  • Cancer Grade
    G4
  • Cancer Stage
    N1
  • Primary Site
    lung
  • Collection Site
    lymph node

PDX model engraftment

PDX model engraftment
HOST STRAIN NAMESITETYPEMATERIALMATERIAL STATUSPASSAGE
nmri
SubcutaneousHeterotopicTissue FragmentFresh/frozen0,10

Model quality control

Model quality control
TECHNIQUEDESCRIPTIONPASSAGE
Histologyhigh concordance between xenograft passages<5,12,24

Immune markers

HLA

HLA
SAMPLE IDHLA-AHLA-BHLA-C
E6R_028d06HLA-A*2:40, HLA-A*24:2
HLA-A*2:1, HLA-A*24:2
HLA-B*18:1, HLA-B*50:2
HLA-B*52:1, HLA-B*39:43
HLA-C*12:3, HLA-C*7:1

Patient treatment

Patient treatment
TREATMENTDOSERESPONSE
Cyclophosphamide, Vincristine, Doxorubicinnot provided + not provided + not providedNot Provided