Date of submission: 14/11/2024

Cutaneous Melanoma

865297-335-R-V1-organoid

Model characterisation

Provided by

Patient-Derived Model Repository

View data at PDMRContact PDMR

License: CC0

Patient / Tumour Metadata

  • Patient Sex
    male
  • Patient Age
    50 - 59
  • Patient Ethnicity
    White
  • Tumour Type
    Metastatic
  • Cancer Grade
    Not provided
  • Cancer Stage
    N2a
  • Primary Site
    skin
  • Collection Site
    lymph node [r axillary]

Model derivation

Model derivation
GROWTH PROPERTIESGROWTH MEDIAPLATE COATINGSTATUSPASSAGESUPPLEMENTSCONTAMINATEDCONTAMINATION DETAILS
Aggregate ClustersDMEM/F12Breast #2Not provided10% FBSNoNone

Model quality control

Model quality control
TECHNIQUEPASSAGEMORPHOLOGICAL FEATURESSTR ANALYSISMODEL PURITY
Fingerprinting
AllNot providedNot providedNot provided
Human Mouse/dna
AllNot providedNot providedNot provided
Histology
AllNot providedNot providedNot provided

Immune markers

Immune markers
SAMPLE IDMMRMSIMutations per mbTMBPloidy
865297-335-R-V1-organoidNot provided
Stable
Not provided
Not provided
Not provided

HLA

HLA
SAMPLE IDHLA-AHLA-BHLA-C
865297-335-R-V1-organoidHLA-A*24:02, HLA-A*26:01
HLA-B*38:01, HLA-B*55:01
HLA-C*03:03, HLA-C*12:03

Patient treatment

Patient treatment
TREATMENTDOSERESPONSE
Pembrolizumab
ChEMBL

Partial Response