Date of submission: 27/05/2022

Rhabdomyosarcoma

SJRHB000026_X1

Model characterisation

Provided by

St. Jude Children's Research Hospital

View data at Contact SJCRH

License: EMBL-EBI

Patient / Tumour Metadata

  • Patient Sex
    female
  • Patient Age
    2 - 9
  • Patient Ethnicity
    Not Provided
  • Tumour Type
    Recurrent
  • Cancer Grade
    Not provided
  • Cancer Stage
    Not provided
  • Primary Site
    pelvis
  • Collection Site
    pelvis

PDX model engraftment

PDX model engraftment
HOST STRAIN NAMESITETYPEMATERIALMATERIAL STATUSPASSAGE
nu/nu
Intramuscle, Hind LegOrthotopicDissociated CellsFresh1
nsg
Intramuscle, Hind LegOrthotopicDissociated CellsFresh0

Model quality control

Model quality control
TECHNIQUEDESCRIPTIONPASSAGE
FingerprintingSTR analysis between passages to confirm xenografts1,2
HistologyH&E, high concordance between xenograft and patient tumor1,2
Wgshigh concordance between xenograft, patient tumor and germline1,2
Weshigh concordance between xenograft and patient tumor1,2
Rna Seqhigh concordance between xenograft and patient tumor1,2
Dna Methylation (850me)high concordance between xenograft and patient tumor1,2